Ciaran Frawley will start at full-back in Ireland’s Six Nations meeting with Wales on Saturday.
Captain Peter O'Mahony returns to the starting team, becoming the ninth Ireland player to reach 50 Guinness Men's Six Nations appearances.
O’Mahony follows Rory Best, Ronan O'Gara, Brian O’Driscoll, Cian Healy, Jonathan Sexton, Conor Murray, John Hayes and Paul O’Connell.
In the absence of Hugo Keenan, Ciaran Frawley starts at full-back. Farrell partners Calvin Nash and James Lowe in the back three for his first test start in green.
Indeed, Bundee Aki returns to the starting XV to continue his midfield partnership with Robbie Henshaw. Whereas, Jamison Gibson-Park and Jack Crowley start at scrum-half and out-half respectively.
In the pack, Andrew Porter, Dan Sheehan and Tadhg Furlong are named in the front row. Meanwhile, Joe McCarthy continues in the second row alongside Tadhg Beirne.
O'Mahony skippers the team from the backrow, alongside Josh van der Flier at openside flanker and Caelan Doris at number eight.
Whereas, Farrell has opted for a 6-2 split on the bench as Ronan Kelleher, Cian Healy, the uncapped Oli Jager, James Ryan, Ryan Baird and Jack Conan provide the reinforcements in the pack.
Backs Conor Murray and Stuart McCloskey complete Ireland's Match Day 23 for the visit of Wales.
Ireland: 15. Ciaran Frawley, 14. Calvin Nash, 13. Robbie Henshaw, 12. Bundee Aki, 11. James Lowe, 10. Jack Crowley, 9. Jamison Gibson-Park, 1. Andrew Porter, 2. Dan Sheehan, 3. Tadhg Furlong, 4. Joe McCarthy, 5. Tadhg Beirne, 6. Peter O'Mahony, 7. Josh van der Flier, 8. Caelan Doris.
Replacements: 16. Ronan Kelleher, 17. Cian Healy, 18. Oli Jager, 19. James Ryan, 20. Ryan Baird, 21. Jack Conan, 22. Conor Murray, 23. Stuart McCloskey
Ireland v Wales
Guinness Men's Six Nations
Aviva Stadium
Saturday February 24, Kick-off: 2:15pm