Social Entrepreneurs Ireland is encouraging people from across the region to “see the challenge and be the change".
Up to 60 places on the Ideas Academy are available for those with an innovative early-stage idea to solve a social problem.
It's a three-month programme that provides participants with the support and direction they need as they take the first steps from idea to action.
Five places are also up for grabs on SEI's prestigious Impact Programme, with applications open until midnight on April 7.
Monaghan man Shane McKenna is the co-founder of Dabbledoo Music and was a Social Entrepreneurs Ireland Impact Awardees in 2016.
He says SEI has given him constant support and encouragement to make a difference through work in music education.
Shane spoke to our reporter Diarmuid Pepper about the SEI Impact programme: