The N2 between the Carrickmacross South turnoff and Clonturk is completely closed following an accident.
There were 2 cars involved in the crash which occurred this afternoon and emergency services were at the scene.
There are no details yet as to whether anyone was injured during the incident.
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Motorists are being diverted onto the old Ardee road (L4922) with no timeline for its reopening confirmed at present.