Cabinet Ministers will discuss the latest setbacks for the vaccination programme when they meet this morning.
The Taoiseach is to be briefed by the HSE and the vaccines taskforce as work continues on redrawing the roll-out plan.
Re-drawn plans to take account of the problems with the availability of the AstraZeneca and Johnson and Johnson vaccines could be ready as early as today.
But senior figures in the Department of Health were not expecting them to be finalised by the time the cabinet meets at 10am.
Taoiseach Micheál Martin will be briefed by the HSE and the head of the vaccine taskforce Brian MacCraith, following on from discussions they had with Health Minister Stephen Donnelly last night.
There's an anxiousness among some cabinet Ministers over what the pause in Johnson and Johnson delivery will mean if it becomes a long term issue, though as just 41,000 doses were due to arrive this month there's hopes the time could be made up.
Minister Donnelly has also said all those who were due to have an AstraZeneca vaccine this week, but had appointments cancelled, will know how they stand in the coming days.
The closure of bookings for mandatory hotel quarantine because of a lack capacity was a risk well flagged by some Ministers and the issue could inflame tensions at the cabinet table again.
Ministers Paschal Donohoe and Michael McGrath will present cabinet with a Stability Programme Update, setting out the big picture financial cost of COVID.
It will forecast GDP growth of 4.5% this year and 5% next year.
But Modified Domestic Demand, a metric the government sees as more reflective of the actual economy, projects a 2.5 per cent growth this year and a jump to 7.5 per cent growth in 2022.
But it will warn that depends on the imperiled vaccine roll-out, and the programme will contain a downside scenario should restrictions stay in place longer than planned.