Parents and carers are being advised not to organise parties, sleepovers, or visits to other people's homes in order to avoid further disruption to in-school learning.
The advice from the HSE Public Health North East and follows the full re-opening of schools this week.
The HSE Public Health North East says it has been working closely with schools in the region to support schools in providing a safe environment for children and young people.
In a statement released this morning, the health body warned that the "stability and rich learning environment" that schools provide could face "further disruption" if covid guidelines are not adhered to.
Parents and carers have been advised to minimise contact with anyone outside of their household, and to refrain from organising parties or sleepovers.
They are also asked to be "conscious of public health guidelines during school runs and pick-ups at school gates".
The HSE Public Health North East says "these actions risk spreading the virus without knowing it", and added that adherence to the covid guidelines is essential even if you have had the vaccine.
Dr Sean Denyer, Specialist in Public Health Medicine at the HSE North East, says "it's important that we don't see a return to playdates, car-pooling, coffee gatherings and birthday parties" as normality returns.
He added that "schools have been doing a heroic job during the pandemic, and parents and carers can help support them to decrease the number of Covid cases in the region".