Lakeland Dairies has been granted permission to erect new silos at its Killeshandra site.
The works will include the demolition of a single story laboratory building to facilitate the construction of two, 20 metre high silos.
The demolition of the existing building is expected to take around two weeks, while the application says there will be a "minimal construction element".
Planning permission for the Church Street factory in Killeshandra follows approval for similar works at Lakeland Dairies' Bailieborough site.