There are calls for "positive discrimination" to reverse the investment imbalance seen in the border and midlands.
New CSO figures show that the after tax incomes in local counties were the lowest across the country.
The Northern and Western Regional Assembly says a decade of underinvestment in key infrastructure projects has seen it lag further behind other parts of Ireland.
Economist with NWRA John Daly says the Government must make a specific effort to address this problem.